Suppose you collect a sample of 11-locus Y-chromosome haplotypes
from 100 men and every haplotype in the sample is
different. We know that the various loci are linked, so it
would not be valid to estimate the population frequency of a
haplotype by assuming the "multiplication rule" most haplotypes
figure to be more common than the product of the frequencies of the
alleles at each locus.
Since multiplication is out, what is a good guess as to
the frequency of each haplotype? 1/100?
haplotype frequency discussion
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