DNAVIEW Immigration Module
First released September 1998. Development and refinement is ongoing.
Kinship in DNAVIEW
Other information about DNAVIEW
Forensic mathematics home page
For further details inquire to Charles Brenner, Ph.D.
Overview of the program
The Immigration suboption of Paternity Case is a link to the Symbolic Kinship Program that runs the Kinship program automatically, without user intervention, through the various loci for which there is data.
Compared to the stand-alone version of the Kinship program, Immigration requires that any DNA typing data for the parties to the inquiry must already have been fed into DNAVIEW.note Once this has been done, Immigration automatically iterates through the Kinship program locus-by-locus, augmenting the user-supplied pedigree definitions with the appropriate symbolic genotype patterns for each locus, evaluating the resultant symbolic likelihood ratio formulas with automatically-computed allele frequencies, and compiling the per-locus results into a brief summary report that includes the cumulative likelihood ratio across all loci.
Evaluation of scenarios is therefore very rapid and simple, and it is practical to experiment with multiple combinations of possible ways that the people in a case may be related.
|Note: Size data can be introduced in various ways including typing in the alleles or sizes, digitizing tablet (i.e. measurement on a gel), or importing Genotyper, Bioimage, Hitachi StarCall, and other file formats.|
First select a case. To create an immigration case, put all the people of interest into the case, without regard to role (child, mother, etc.) For the race list ("edit race list"), choose the main race to use for calculation.
Then Immigration becomes an available sub-menu option. Select it and the program collects all genotype data for the people in question.
If you refuse to select a database (hit ENTER with no selection), then you will subsequently be prompted to supply frequencies. So this is a viable option.
Menu of Immigration options
|(a)||Type in (or edit) scenario 1||(a), or (p) create a pedigree definition for evaluation.
In (a), an editing screen is opened. On the top is a summary of the genotypic patterns of the people. The bottom is space for you to type in a Kinship-type pedigree/locus definition. Do not include genotype information; that will be provided automatically, and locus-by-locus for all loci.
Type ctrl-e when finished entering the pedigree/locus.
|(b)||Display the raw sizes (for eyeball check)||displays the raw data on the screen so you can proof-read it|
|(c)||Find formulas and evaluate for all loci||Calculations are performed automatically across all loci. The summary (d) is then displayed.|
|(d)||Show summary of calculation||Show the summary on the screen, a 1-line-per locus, plus overall
likelihood ratio, for the last scenario computed.
The summary is NOT appended to the final report unless you specifically choose to have it be:
|(e)||Add summary of calculation to report||Add summary for this scenario to the report.|
|(f)||Add scenario to/ modify the pick list||Pick list maintenance see (p).
The pick list is permanently saved on the hard drive, and gives you a way to save and re-use frequent pedigree definitions.
The "Add" command is really general maintenance, which permits